| # | VW | W | Artiest | Titel | Label | Distributeur | HP |
|---|
| 1 | 2 | 15 | Thor! | Een tocht door het donker | CAPITOL | EMI | 1 |
| 2 | 1 | 5 | P!nk | Dear Mr. President | LAFACE | SONY BMG | 1 |
| 3 | 3 | 10 | Clouseau | Vonken & vuur | CAPITOL | EMI | 1 |
| 4 | 5 | 12 | Akon feat. Eminem | Smack That | SRC | UNIVERSAL | 4 |
| 5 | 4 | 18 | Snow Patrol | Chasing Cars | FICTION | UNIVERSAL | 3 |
| 6 | 6 | 6 | Nelly Furtado | All Good Things (Come To An End) | GEFFEN | UNIVERSAL | 6 |
| 7 | 7 | 11 | Christina Aguilera | Hurt | RCA | SONY BMG | 7 |
| 8 | 8 | 6 | Gwen Stefani | Wind It Up | INTERSCOPE | UNIVERSAL | 8 |
| 9 | 37 | 2 | Eric Prydz vs. Floyd | Proper Education | ARS | EMI | 9 |
| 10 | 12 | 6 | Milk Inc. | No Angel | ANTLER-SUBWAY | EMI | 10 |
| 11 | 15 | 8 | Fergie feat. will.i.am | Fergalicious | A&M | UNIVERSAL | 11 |
| 12 | 10 | 11 | James Morrison | You Give Me Something | POLYDOR | UNIVERSAL | 7 |
| 13 | 32 | 2 | Nienke | Het huis Anubis | STUDIO 100 | UNIVERSAL | 13 |
| 14 | 11 | 10 | Red Hot Chili Peppers | Snow (Hey Oh) | WARNER BROS. | WARNER | 9 |
| 15 | NEW | 1 | Mega Mindy | Ik ben Mega Mindy | STUDIO 100 | UNIVERSAL | 15 |
| 16 | 9 | 19 | Kaye Styles | Prison Break Anthem | MOSTIKO | CNR | 3 |
| 17 | 19 | 15 | Gebroeders Ko | Boten Anna | ARS | EMI | 8 |
| 18 | 13 | 20 | Scissor Sisters | I Don't Feel Like Dancin' | POLYDOR | UNIVERSAL | 1 |
| 19 | 21 | 15 | Marco Borsato & Lucie Silvas | Everytime I Think Of You | MERCURY | UNIVERSAL | 5 |
| 20 | 14 | 13 | The Pussycat Dolls | I Don't Need A Man | A&M | UNIVERSAL | 7 |
| 21 | 20 | 7 | Samson & Gert | Lieve Samson | STUDIO 100 | UNIVERSAL | 7 |
| 22 | 31 | 5 | P. Diddy feat. Christina Aguilera | Tell Me | BAD BOY | WARNER | 22 |
| 23 | 16 | 12 | Beyoncé | Irreplaceable | COLUMBIA | SONY BMG | 13 |
| 24 | 17 | 9 | Laura Lynn & Marva | Rode rozen in de sneeuw | ARS | EMI | 5 |
| 25 | 24 | 10 | Justin Timberlake feat. T.I. | My Love | JIVE | SONY BMG | 17 |
| 26 | 26 | 8 | Take That | Patience | POLYDOR | UNIVERSAL | 24 |
| 27 | 25 | 9 | Robbie Williams | Lovelight | CHRYSALIS | EMI | 18 |
| 28 | 22 | 38 | Marco Borsato | Rood | UNIVERSAL | UNIVERSAL | 1 |
| 29 | 18 | 20 | Fedde Le Grand | Put Your Hands Up 4 Detroit | ARS | EMI/ASTRAL | 14 |
| 30 | 28 | 11 | Shakira feat. Carlos Santana | Illegal | EPIC | SONY BMG | 22 |
| 31 | 29 | 2 | Holly Dolly | Dolly Song (Ieva's Polka) | DIGIDANCE | DIGIDANCE | 29 |
| 32 | NEW | 1 | Willy Sommers | Jij bent alles voor mij | MAGIC | EMI | 32 |
| 33 | 23 | 23 | Bob Sinclar & Cutee-B feat. Dollarman & Big Ali & Makedah | Rock This Party (Everybody Dance Now) | 541/NEWS | PIAS/NEWS | 1 |
| 34 | 27 | 5 | Damien Rice | 9 Crimes | 14TH FLOOR | WARNER | 26 |
| 35 | 38 | 6 | Bodyrox feat. Luciana | Yeah Yeah | ARS | EMI | 33 |
| 36 | 35 | 14 | P. Diddy feat. Nicole Scherzinger | Come To Me | BAD BOY | WARNER | 25 |
| 37 | NEW | 1 | U2 | Window In The Skies | ISLAND | UNIVERSAL | 37 |
| 38 | NEW | 1 | Gia Farrell | Hit Me Up | ATLANTIC | WARNER | 38 |
| 39 | 30 | 11 | Sean Paul feat. Keyshia Cole | (When You Gonna) Give It Up To Me | ATLANTIC | WARNER | 22 |
| 40 | 34 | 18 | ReBorn | Don't Ever Go | ARS | EMI | 5 |
| 41 | NEW | 1 | Cascada | Everytime We Touch | UNIVERSAL | UNIVERSAL | 41 |
| 42 | 40 | 21 | Milk Inc. | Run | ANTLER-SUBWAY | EMI | 7 |
| 43 | 43 | 6 | Rihanna | We Ride | DEF JAM | UNIVERSAL | 40 |
| 44 | 42 | 7 | Kate Ryan | All For You | 2BRAINS | EMI | 37 |
| 45 | 45 | 4 | KetnetBand | Gekke Pinguïndans | EMI | EMI | 38 |
| 46 | 36 | 10 | Daan | The Player | PIAS | PIAS | 11 |
| 47 | NEW | 1 | Sharam | PATT (Party All The Time) | ARS | EMI | 47 |
| 48 | 41 | 18 | Justin Timberlake | SexyBack | JIVE | SONY BMG | 3 |
| 49 | 47 | 15 | The Kooks | She Moves In Her Own Way | VIRGIN | EMI | 29 |
| 50 | 46 | 10 | Wendy Van Wanten | (Am I A) Woman In Love | ARS | EMI | 20 |
